In a perfect world, every component would be manufactured exactly to spec. But perfection drives costs higher so it makes sense to accommodate small variations — tolerances — as long as they do not compromise the finished assembly. But there is a catch. Tight-fitting parts from accumulated “stacked tolerances” can make assembly difficult and slow and even degrade the operation of the finished device. A cost-effective way to address stacked tolerances is to use a dry lubricant based on polytetrafluoroethylene (PTFE). Dry lubricants improve the performance of a finished device, reducing the coefficient of friction. This translates into a 25-30% reduction in actuation forces. Many medical devices would not be commercially viable without a dry lubricant.